ea0025p179 | Endocrine tumours and neoplasia | SFEBES2011
Meredith Suzanne
, Babur Muhammad
, Begum Ghazala
, Telfer Brian
, Gieling Roben
, Dean Emma
, Dive Caroline
, Williams Kaye
, White Anne
Small cell lung cancer (SCLC) is highly aggressive with a particularly poor prognosis. This is due to tumours quickly metastasising and developing chemoresistance. SCLC tumours possess neuroendocrine properties in that they secrete prohormones such as pro-opiomelanocortin (POMC) and pro-gastrin releasing peptide (pro-GRP). These can be detected in the circulation and therefore have potential as biomarkers for prognosis and relapse. The aims of this study are; i) develop a mode...